Senior Scientist - Experimental Protein Design for Target Discovery

Join Amgen’s Mission of Serving Patients as a Senior Scientist - Experimental Protein Design for Target Discovery. Build and lead high-throughput platforms for binder generation, translating computational protein designs into experimentally validated minibinders and antibodies across diverse pre-discovery targets.

Requirements

• Translate computational protein designs into experimentally testable minibinders and antibodies across multiple targets in parallel.
• Lead high-throughput workflows for binder expression, purification, and characterization, including development of cellular assays for binder–target evaluation.
• Partner with molecular biology teams to establish construct generation and binder library production workflows, enabling both individual binder characterization and scalable pooled library screening.
• Develop strategies to format de novo binders into appropriate modalities (e.g., multispecifics) to enable testing of biological hypotheses.
• Analyze and interpret experimental data to guide iterative design-build-test cycles.

Benefits

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• Discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible