Korro is a biopharmaceutical company seeking an experienced Senior Scientist, Computational Biology to join its Data Science team and contribute to research and translational programs. The successful candidate will operate as an analytical generalist, comfortable moving between target validation, NGS/omics analysis, assay analytics, and translational support for oligonucleotide therapeutics pipeline.
Requirements
- Drive computational biology analyses across Korro's research pipeline, including target validation, mechanism-of-action studies, and characterization of RNA editing activity in preclinical models.
- Design, execute, and interpret NGS-based experiments (RNA-seq, variant calling, targeted amplicon sequencing) in support of oligonucleotide design, screening, and pharmacology workstreams.
- Partner with platform biology, chemistry, and pharmacology teams to translate experimental questions into rigorous analytical workflows and to communicate results in a form that informs program decisions.
- Develop and maintain reproducible analysis pipelines in R and/or Python, leveraging existing Data Science infrastructure (Posit Connect, MLflow, containerized environments, AWS).
- Contribute analytical support to the preclinical-to-clinical translational handoff for our GalNAc-conjugated programs, including PK/PD characterization and biomarker analysis as programs mature.
- Collaborate with cross-functional stakeholders to scope new analyses, set realistic timelines, and deliver results that are technically sound and decision-ready.
- Mentor junior scientists and contractors on best practices in scientific computing, reproducibility, and statistical rigor.
- Share findings through internal presentations and contribute to the scientific community through publications or presentations as appropriate.
Benefits
- Competitive compensation
- Equity-based compensation
- Comprehensive benefits package
- Medical, dental, vision
- 401(k) retirement plan
- Life insurance
- Dependent care flexible spending account
- Company-funded health savings account
- Free parking
