Associate Director, Upstream Biologics Drug Substance
Disc MedicineWatertown, Massachusetts, United States
Posted November 4, 2025
157250 - 212750 USD year
Full Time
About the Company
Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases.
Job Description
Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA. As an Associate Director, Upstream Biologics Drug Substance, you will lead upstream process development for biologic programs from preclinical through late-stage development, ensuring scalability, robustness, and product quality.
Requirements
- Lead upstream process development for biologic programs from preclinical through late-stage development, ensuring scalability, robustness, and product quality.
- Oversee cell line development, media/feed optimization, bioreactor scale-up, and process parameter definition.
- Lead tech transfer to CDMO manufacturing sites, ensuring successful execution at pilot and large scale.
- Partner with analytical, downstream, and manufacturing sciences teams to ensure seamless integration of drug substance activities.
Benefits
- Comprehensive benefits
- Competitive compensation packages
