Contract Process Development Associate II

Keros Therapeutics is seeking a Contract Process Development Associate II to provide support in early stages of process development and act as an interface with Research and CMC organizations. The role will involve executing and developing stage appropriate downstream processes for novel protein therapeutics.

Requirements

• Hands-on execution, and optimization of protein purification processes
• Generate and analyze process and analytical data
• Execute routine scale down protein purification
• Perform analyses including UV-Vis Spectroscopy, SDS-PAGE, SE-HPLC, LAL, host cell-DNA, host cell protein
• Buffer preparation and aseptic technique
• Drug substance and protein intermediate inventory management
• Work within the DSP group to explore novel purification processes
• Perform small-scale studies and pilot scale purification studies
• Apply DOE methods to purification activities
• Executing protocols, interpretation of data, and report generation
• Work with Co-Ops and helping them in their planning and activities as needed
• Maintain laboratory notebooks and digital records
• Present data at process development and CMC department meetings
• Operate and troubleshoot process equipment
• Chromatography, TFF including, UD/DF, micro filtration, nano filtration, and filtration
• Process scaling and/or technology transfer

Benefits

• health insurance
• retirement plan
• paid time off