Team Leader / Research Leader (Computational Drug Design), London, Lausanne

Isomorphic Labs is a cutting-edge biotech company using AI to solve all disease. We're seeking a Team Leader / Research Leader to spearhead the design of novel small molecule therapeutics using our AI-first approach.

Requirements

• PhD in Computational Chemistry, Medicinal Chemistry, Synthetic Chemistry, or a related scientific field.
• 8+ years' professional experience in pharma, biotech, or CRO environment.
• Proven experience leading computational chemistry strategy and execution for multiple drug discovery programs.
• Strong expertise in virtual screening, ligand and structure-based drug design using physics-based and AI/ML methods.
• Proven track record of developing QSAR models using ML or deep learning methods.
• Expertise in writing and implementing Python scripts for analysis and tool development, and/or utilising pipelining tools to support cheminformatics and design workflows.
• Strong knowledge of medicinal chemistry principles including ADMET and DMPK.
• Knowledge of modalities such as PROTACs, molecular glues, PPI inhibitors or ADCs.
• Genuine passion and enthusiasm for applying AI/ML to drug design and how this can transform the field.
• Demonstrated success managing external collaborations (industry/CROs) and working effectively in cross-functional environments.
• Growth mindset, adaptability, and eagerness to learn new concepts and techniques.

Benefits

• Flexible working hours
• Generous parental leave
• Tuition reimbursement
• Relocation assistance
• Hybrid working model (3 days in office, 2 days remote)