Senior Director, AI and Data Science (Drug Discovery and R&D Enablement)

Lexeo is seeking a Senior Director, AI and Data Science to accelerate decision-making across discovery, development, and operational execution using applied AI/ML solutions. The role requires a leader who can build, validate, and operationalize models using real-world biopharma data.

Requirements

• Define and execute Lexeo's applied AI/ML roadmap across discovery and development
• Deliver solutions that are internal-only and external-facing
• Establish best practices for model lifecycle management
• Lead development and selection of appropriate ML approaches
• Build and oversee predictive analytics using real-world data
• Apply techniques to amplify signal-to-noise in smaller datasets
• Guide strategy for synthetic control arms and comparable approaches
• Translate drug discovery and translational questions into testable analytical hypotheses
• Partner with stakeholders across R&D, CMC, Clinical, Safety, and IT/Security
• Liaise with external partners to evaluate tools and deliver solutions
• Improve internal processes through automation and analytics
• Establish practical governance for data quality, documentation, and fit-for-use standards

Benefits

• Comprehensive health insurance
• 401k Matching
• Generous Paid Time Off
• Relocation Assistance