Senior Scientist II - Translational Pathologist
MacroGenicsRockville, Maryland, United States
Posted March 17, 2026
Full Time
About the Company
MacroGenics specializes in the discovery and development of next‑generation antibody‑based therapeutics, with a robust pipeline focused on oncology, autoimmune disorders, and infectious diseases. The company leverages cutting‑edge technologies such as bi‑specific antibodies, Fc optimization, and monoclonal antibody platforms to create innovative medicines that address unmet medical needs. MacroGenics has forged strategic partnerships with leading pharmaceutical and biotechnology firms worldwide, amplifying its research impact and accelerating product development. With a dedicated team of over 300 professionals, the company fosters a culture of innovation, open communication, and teamwork, positioning employees as its most valuable asset.
Job Description
The Senior Scientist II - Translational Pathologist will support tissue-based pathology activities across MacroGenics’ antibody-drug conjugate (ADC) and immunotherapy programs.
Requirements
- MD, DVM, or PhD with formal training in pathology, histopathology, or a closely related discipline.
- 3–5 years of experience in biomarker target validation, translational research, biotechnology, pharmaceutical, or CRO environments.
- Hands-on experience with histopathologic and immunohistochemical tissue evaluation.
- Excellent pathology diagnostic skills.
- Skilled in mIF development, validation and spatial analysis.
- Experience with digital pathology and image analysis platforms (e.g., HALO, QuPath).
- Strong scientific writing and communication skills.
- Experience supporting ADC, immuno-oncology, or T-cell engager programs.
- Experience working with AI/ML algorithms for digital pathology analysis.
- Exposure to GLP toxicology studies and nonclinical safety assessments.
- Experience working with external CROs.
Benefits
- Generous Paid Time Off
- 401k Matching
- Retirement Plan
