Manifold Bio is a pioneering tissue-specific medicines company focused on developing targeted biologics using a high-throughput in vivo discovery engine. This innovative approach combines massively multiplexed in vivo screening with AI-powered design to optimize pharmacokinetics and biodistribution, solving previously intractable challenges for tissue-specific delivery. By generating rich datasets, Manifold Bio accelerates the development of effective therapeutics, paving the way for faster patient access.
Open Positions
Director, People & Talent Operations
10+ years of HR leadership experience, with a focus on high-growth startups and comprehensive HR operations
Director, Oligo Team Lead
PhD in a relevant field and 10+ years of experience in industry drug-discovery programs
AI/ML Scientist – Protein Foundation Models
2+ years of experience in pretraining and/or fine-tuning protein foundation models, strong familiarity with AlphaFold architecture and training methodology, and experience with large-scale model training
Sr. Director, Biotherapeutics
10+ years of experience in biotherapeutics, protein engineering, and team leadership
Scientist, cDNA Display
PhD or equivalent experience in protein biochemistry, molecular biology, or related field, hands-on experience with cell-free selection systems, and strong molecular biology fundamentals
AI/ML Scientist
PhD in Machine Learning or related field, 5+ years of industry experience, and expert-level proficiency in PyTorch and/or JAX
AI/ML Research Engineer
Bachelor's or Master's degree, 2+ years of experience with PyTorch and/or JAX, strong proficiency in Python scientific computing stack