As Executive Director of Process Chemistry, you will lead the global API strategy across Praxis' portfolio, ensuring scientific excellence, regulatory alignment, and supply chain scalability from IND through commercial launch. This is a mission-critical role for a bold and visionary leader committed to accelerating patient impact.
Requirements
- Own and drive the global API strategy across Praxis' portfolio, ensuring scientific excellence, regulatory alignment, and supply chain scalability from IND through commercial launch.
- Lead the design, development, and industrialization of robust, phase-appropriate drug substance processes—championing modern technologies such as continuous flow, biocatalysis, and digital process design.
- Act as a thought leader and decision-maker in CMC governance forums, ensuring tight alignment between drug substance strategy and broader program objectives.
- Build and lead a high-performing, multidisciplinary ecosystem of internal talent and external partners (CROs/CDMOs), holding to the highest standards of execution, accountability, and innovation.
- Define and execute vendor strategy, including partner selection, technical oversight, contract negotiation, and performance governance.
- Ensure seamless integration with Analytical, Formulations, Regulatory, Quality, and Clinical Supply—driving unified CMC plans that anticipate risk and accelerate timelines.
- Represent Praxis externally with regulators, partners, and scientific communities—contributing to our reputation as a science-driven, execution-focused innovator in CNS therapeutics.
Benefits
- 99% of the premium paid for medical, dental and vision plans
- Company-paid life insurance, AD&D, disability benefits, and voluntary plans
- Match dollar-for-dollar up to 6% on eligible 401(k) contributions
- Long-term stock incentives and ESPP
- Discretionary quarterly bonus
- Flexible wellness benefit
- Generous PTO, paid holidays and company-wide shutdowns
