Senior Scientist, Drug Metabolism & Pharmacokinetics (DMPK)

We are seeking a motivated and skilled Senior Scientist to join the Nonclinical Development group, contributing to the DMPK function in support of exploratory and IND-enabling programs across Prime Medicine’s pipeline.

Requirements

• D. in pharmacokinetics, pharmaceutical sciences, pharmacology, biochemistry, or a related discipline
• 6+ years of cumulative experience
• Demonstrated experience with in vivo PK studies in preclinical models and proficiency in NCA using Phoenix WinNonlin or equivalent software
• Familiarity with regulatory expectations for nonclinical DMPK assessments and bioanalytical assay development
• Demonstrated ability to coordinate with external CROs, including scientific guidance, protocol development, and data review
• Strong written and verbal communication skills; ability to present complex DMPK data clearly to multidisciplinary audiences
• Highly self-motivated, collaborative, and organized, with the ability to manage multiple priorities independently in a fast-paced matrix environment

Benefits

• Comprehensive Total Rewards package with robust health, financial, and wellness benefits
• Generous paid time off, wellness days, and company-wide recharge breaks
• 401(k) match
• Equity programs