Principal Scientist, Analytical Chemistry

Revolution Medicines is seeking a scientifically talented and highly motivated individual to join our Integrated Discovery Research team as Principal Scientist, Head of Analytical Chemistry. This role will drive analytical chemistry strategy and execution within the Medicinal Chemistry function, supporting drug discovery programs from early hit identification through lead optimization and candidate selection.

Requirements

• Ph.D. in Analytical or Organic Chemistry (or related discipline)
• 12+ years of industry experience
• Demonstrated expertise in advanced analytical method development, troubleshooting, and problem-solving in small molecule drug discovery
• Strong hands-on experience with chromatographic and spectroscopic techniques, including LC/MS, HPLC, SFC, and NMR
• Proven experience supporting drug discovery programs across multiple modalities, including small molecules, peptides, and antibody–drug conjugates (ADCs)
• Strong problem-solving skills with sound technically driven decision-making ability
• Excellent communication skills and the ability to drive cross-disciplinary partnerships
• A track record of innovation and execution in fast-paced, data-driven research environments

Benefits

• Competitive cash compensation
• Robust equity awards
• Strong benefits
• Significant learning and development opportunities