Director, AI Small Molecule Drug Design
SystimmuneRedmond, Washington, United States
Posted January 27, 2026
200000 - 250000 USD
Full Time
About the Company
Systimmune Inc., founded in 2014 in Redmond, WA, is a bio-pharmaceutical company specializing in the development of novel bi-specific and tri-specific antibodies, as well as antibody-drug conjugates (ADCs) for cancer treatment. The company focuses on systematically intervening in the solid tumor micro-environment to either directly attack tumors or activate the immune system. Led by experienced immuno-oncology scientists, Systimmune leverages advanced technology platforms to create world-class antibody-based drug therapies.
Job Description
SystImmune is hiring a Director to lead its AI-enabled small molecule design function. The role involves defining, building, and leading the function, and applying advanced AI methodologies to generate novel small molecules and predict target interactions.
Requirements
- PhD or equivalent in Computational Chemistry, Bioinformatics, Biophysics, Machine Learning or related field
- 10+ years of experience applying computational chemistry and AI to small molecule drug design
- Hands-on expertise in structure-based drug design, ligand-based design, generative methods, and predictive modeling
- Strong technical fluency in relevant tools and programming languages such as Python, R, or C++, and experience with machine learning frameworks (e.g., TensorFlow, PyTorch)
Benefits
- 100% paid employee premiums for medical/dental/vision
- STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years
- 15 PTO days per year, sick leave, plus 11 paid holidays and MORE
