Principal Scientist, CDx IHC Development
SystimmuneRedmond, Washington, United States
Posted March 28, 2026
130000 - 160000 USD
Full Time
About the Company
Systimmune Inc., founded in 2014 in Redmond, WA, is a bio-pharmaceutical company specializing in the development of novel bi-specific and tri-specific antibodies, as well as antibody-drug conjugates (ADCs) for cancer treatment. The company focuses on systematically intervening in the solid tumor micro-environment to either directly attack tumors or activate the immune system. Led by experienced immuno-oncology scientists, Systimmune leverages advanced technology platforms to create world-class antibody-based drug therapies.
Job Description
SystImmune is a leading clinical-stage biopharmaceutical company seeking a Principal Scientist to lead CDx IHC development initiatives, ensuring compliance with global regulatory and quality standards.
Requirements
- PhD in Pathology, Immunology, Molecular Biology, or related life science field
- 8–12+ years of industry experience in CDx, IVD, or biomarker assay development
- Proven experience leading IHC assay development and analytical validation
- Strong knowledge of design controls and QMS (21 CFR Part 820, ISO 13485)
- Experience supporting clinical trials and CDx regulatory submissions
- Strong understanding of IHC scoring methods (TPS, CPS, H-score)
- Experience working in oncology biomarker development environments
Benefits
- 100% paid employee premiums for medical/dental/vision
- STD, LTD, a 401(k) plan with a 50% company match of up to 3%
- 15 PTO days per year, sick leave, plus 11 paid holidays