Senior/Principal Scientist – AI/ML Protein & Antibody Drug Discovery

SystImmune is a leading biopharmaceutical company seeking a Senior/Principal Scientist to drive the design and implementation of advanced machine learning models and data infrastructure to accelerate therapeutic discovery across its biologics pipeline.

Requirements

• Ph.D. in Computational Biology, Computer Science, Bioinformatics, Structural Biology, or a related field
• 5+ years of experience in AI/ML applied to protein or antibody drug discovery in an industry or translational research setting
• Proven track record of developing and applying ML models for antibody/protein optimization, structure-function modeling, or drug design
• Proficient in Python and deep learning frameworks such as PyTorch or TensorFlow
• Experience with LLMs, GNNs, and relevant tools for structure and sequence analysis (e.g., AlphaFold, Rosetta, DiffDock)
• Strong understanding of antibody engineering principles, therapeutic design challenges, and developability constraints

Benefits

• 100% paid employee premiums for medical/dental/vision
• STD
• LTD
• 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years
• 15 PTO days per year
• Sick leave
• 11 paid holidays
• MORE