Tango Therapeutics is seeking an innovative and collaborative leader to serve as Vice President, Safety and Pharmacovigilance.
Requirements
- Lead and oversee all pharmacovigilance and risk management activities for Tango’s clinical programs
- Develop and execute comprehensive safety science strategies for oncology drug development programs from preclinical through post-market surveillance
- Provide safety expertise and risk-benefit assessments to support go/no-go decisions for oncology programs
- Represent Tango in interactions with health authorities, including preparing and presenting safety data in regulatory meetings
- Provide medical safety expertise and leadership across all clinical development activities, including protocols, CSRs, IBs, ICFs, and regulatory briefing books
- Oversee signal detection, safety surveillance, and benefit-risk assessments, implementing risk mitigation strategies as needed
- Direct the preparation and review of key safety documents, including DSURs, SUSARs, periodic and annual safety reports, and regulatory communications
- Develop and manage PV budgets, ensuring alignment with corporate objectives
- Oversee the development and execution of safety processes, standards, and technologies to improve efficiency, scalability, and scientific quality
- Direct the preparation of safety sections for regulatory submissions including INDs, NDAs, BLAs, and periodic safety reports
- Oversee the development of safety monitoring plans and data safety monitoring boards for clinical trials
- Build and lead a high-performing global safety science organization
- Lead cross-functional safety teams and collaborate with clinical development, regulatory affairs, medical affairs, and commercial teams
- Mentor and develop safety professionals, fostering a culture of scientific rigor and patient focus
- Represent the company at regulatory meetings, scientific conferences, and industry forums
- Collaborate with external partners including CROs, academic institutions, and regulatory consultants
- Champion patient safety as a core organizational value
Benefits
- Generous Paid Time Off
- 401k Matching
- Retirement Plan
- Health insurance
- Dental insurance
- Vision insurance
- Life insurance
- Short-term disability insurance
- Long-term disability insurance
