Scientist / Senior Scientist, DMPK

We are seeking a Scientist or Senior Scientist to join our Drug Metabolism and Pharmacokinetics (DMPK) team in the Bay Area or San Diego. The successful candidate will provide DMPK support to our therapeutic programs, working on small molecules, antisense oligonucleotides, therapeutic proteins, and gene therapy.

Requirements

• Serve as the DMPK representative on cross-disciplinary preclinical project teams
• Plan, manage, and oversee ADME and PK studies
• Partner with Medicinal Chemistry to develop ADME- and PK-driven SAR strategies
• Collaborate with Pharmacology and the internal DMPK bioanalysis group
• Calculate the projected efficacious human dose
• Provide DMPK support to early-stage discovery programs
• Advise and train the DMPK bioanalysis team
• Stay current on emerging DMPK science and best practices