Senior Principal Scientist | Antibody-siRNA Bioanalytical & Biodistribution Strategy Lead
AmgenUnited States
Posted March 11, 2026
183958 - 204835 USD
Full Time
About the Company
Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Job Description
Amgen is seeking a Senior Principal Scientist to lead the strategy and execution of innovative bioanalytical platforms to measure antibody-siRNA conjugates. The role will involve leading teams, collaborating with multidisciplinary teams, and contributing to regulatory applications.
Requirements
- Doctorate degree in pharmacology, biochemistry, or a related-scientific discipline and 3 years of industry experience
- Master’s degree in pharmacology, biochemistry, or a related-scientific discipline and 6 years of industry experience
- Bachelor’s degree in pharmacology, biochemistry, or a related-scientific discipline and 8 years of industry experience
- Extensive knowledge of antibody-siRNA conjugate ADME and pharmacokinetics
- Experience investigating biodistribution and metabolism of siRNA conjugated to a tissue-targeting ligand
- Expertise in antibody-siRNA bioanalytical approaches and considerations
- Exceptional written and verbal communication skills
- Experience with regulatory filings for antibody-siRNA conjugates and/or other targeted delivery siRNA therapeutics
Benefits
- Comprehensive employee benefits package
- Discretionary annual bonus program
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models
