Senior Scientist I, DMPK

Arrowhead Pharmaceuticals is seeking a Senior Scientist, DMPK to play a key role in advancing our growing pipeline of RNAi-based therapeutics.

Requirements

• PhD in Pharmacometrics, Drug Metabolism, Pharmaceutical Sciences, or a related discipline with at least 3 years of industry experience.
• Deep and broad expertise in DMPK, with working knowledge of nucleotide or oligonucleotide drug metabolism and distribution highly desired.
• Hands-on experience with in vitro ADME assays, in vivo PK studies, drug–drug interaction (DDI) evaluations, and Phoenix WinNonlin.
• Experience with LC–MS/MS and HRMS, ideally applied to oligonucleotide therapeutics.
• Strong background in organic chemistry, biochemistry, and drug biotransformation.
• Demonstrated experience in drug development and understanding of regulatory processes.
• Excellent interpersonal, verbal, and written communication skills, with the ability to interpret and present complex scientific data clearly.

Benefits

• Competitive salaries
• Excellent benefit package