Executive Director, Head of Toxicology

Centessa Pharmaceuticals is seeking an Executive Director/Head of Toxicology to provide scientific and strategic leadership for nonclinical safety across discovery and development programs, with an emphasis on small-molecule therapeutics.

Requirements

• PhD in Toxicology, Pharmacology, Pathology, DVM, or related discipline; board certification (e.g., DABT, ERT) preferred
• 18+ years of experience in pharmaceutical or biotechnology R&D with a strong track record in nonclinical and regulatory toxicology
• Proven ability to function as an upward-facing nonclinical leader and generalist
• Deep expertise supporting small-molecule programs across discovery, IND-enabling, and early clinical development
• Strong working knowledge of national and international GLP guidelines
• Experience preparing and reviewing nonclinical sections of global regulatory submissions and engaging with health authorities (FDA, EMA)
• Excellent communication and influencing skills, with the ability to partner effectively across Early Development, Research, and Regulatory functions in a fast-paced environment

Benefits

• 401(k) plan
• Company-sponsored medical, dental, vision, and life insurance
• Generous paid time off
• Health and wellness program