AI/ML Scientist – Protein Foundation Models

Manifold Bio is looking for an AI/ML Scientist to join their team in training protein foundation models on proprietary experimental datasets. The successful candidate will work alongside the existing model training team to accelerate the development of foundation models and improve mBER's design capabilities.

Requirements

• Advance the team's ongoing foundation model training efforts
• Bring depth in training methodology, architecture selection, and optimization
• Develop and scale training pipelines for distributed, multi-GPU and multi-node training runs
• Integrate foundation model outputs into mBER to improve binder design success rates
• Design and execute ML experiments with clear hypotheses
• Establish best practices for mixed-precision training, gradient checkpointing, and computational efficiency at scale
• Produce clear documentation and analysis supporting architecture and training decisions

Benefits

• Competitive salary and benefits
• Opportunity to work with a world-class team
• Chance to directly impact real drug discovery programs