Sr. Scientist, Peptide & Oligonucleotide API Development

We are seeking a highly motivated Scientist to join our API Development group within CMC to develop peptide and oligonucleotide synthetic processes and complexation to large-molecule therapeutics. The successful candidate will contribute to the development of novel hybrid therapeutics and emerging modalities, lead and support the development, scale-up, and management of manufacturing and purification processes, and collaborate cross-functionally to ensure successful technology transfer from laboratory to manufacturing.

Requirements

• PhD in Chemistry with relevant industry or postdoctoral experience
• MS in Chemistry with 3+ years of relevant pharmaceutical/process development experience
• BS/BA in Chemistry with 5+ years of relevant experience, including API manufacturing
• Proven experience in process development, optimization, and scale-up of peptide and/or oligonucleotide synthesis
• Strong expertise in purification strategies, including reverse-phase, ion-exchange, and/or affinity chromatography
• Experience in peptide/oligonucleotide CMC development and GMP manufacturing
• Hands-on experience in bioconjugation chemistry and downstream purification
• Solid understanding of cGMP requirements for drug substance development
• Ability to serve as a technical liaison across discovery, preclinical, quality, regulatory, and supply chain teams
• Strong laboratory skills and experience with a wide range of scientific equipment and tools
• Excellent analytical, organizational, communication, and presentation skills
• Demonstrated ability to manage multiple priorities and meet deadlines with accuracy and efficiency
• Proven ability to collaborate effectively within cross-functional teams

Benefits

• Retirement savings plan (with company match)
• Paid vacation
• Holiday and personal days
• Paid caregiver/parental and medical leave
• Health benefits to include medical, prescription drug, dental and vision coverage