Senior Director, Clinical Pharmacology
Nuvalent, Inc.Cambridge, Massachusetts, United States
Posted March 24, 2026
270000 - 295000 USD
Full Time
About the Company
Nuvalent is working to create selective medicines designed to address the needs of patients with cancer.
Job Description
The Senior Director, Clinical Pharmacology will lead Nuvalent’s clinical pharmacology strategy across all development programs, including late-stage registrational efforts and emerging early-phase assets.
Requirements
- Serve as the clinical pharmacology lead and develop and execute strategies to support Phase 1, registrational, and post-marketing studies
- Drive the integration of PK, PD, safety, and efficacy data to inform dose selection, dose modification, and labeling recommendations
- Represent clinical pharmacology in interactions with FDA and other global regulators
- Partner closely with DMPK, Non-clinical Toxicology, Clinical Development, Biostatistics, CMC, and Regulatory Affairs
- Oversee population PK modeling, PK/PD modeling, and exposure–response analyses for efficacy and safety
- Guide quantitative pharmacology approaches supporting optimal dosing in patients
Benefits
- Medical, dental, and vision insurance
- 401(k) retirement savings plan
- Generous paid time off
- Summer and winter company shutdown
