Senior Director, Drug Metabolism and Pharmacokinetics (DMPK)

The Senior Director, Drug Metabolism and Pharmacokinetics (DMPK) will oversee DMPK strategy and design, implement, and interpret DMPK studies to support IND, CTA, and NDA filings.

Requirements

• 12+ years of industry experience in DMPK, including leadership responsibility.
• D. in Pharmaceutical Sciences, Pharmacokinetics, Biochemistry, Chemistry, or related discipline; postdoctoral training preferred.
• Proven track record supporting programs from discovery through clinical development; experience with IND and NDA/MAA submissions strongly preferred.
• Demonstrated experience supporting small‐molecule oncology therapeutics, ideally kinase inhibitors or targeted therapies.
• Hands‐on expertise with ADME assays and mechanistic metabolism studies and PK/PD modeling and simulation, proficient in Phoenix WinNonlin, preferred: experience with GastroPlus modeling.
• Experience contributing to late‐stage development and NDA filings, preferably in oncology.
• Prior experience supporting products approaching commercial launch.
• Experience with vendor/CRO oversight and budget management.

Benefits

• Medical, dental, and vision insurance
• 401(k) retirement savings plan
• Generous paid time off
• Summer and winter company shutdown