Principal UI Engineer (Boston, MA)
OpenEye, Cadence Molecular SciencesBoston, Massachusetts, United States
Posted January 23, 2026
117600 - 218400 USD
Full Time
About the Company
OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design based on decades of delivering rapid, robust, and scalable software, toolkits, and technology and design services across the drug discovery process. Our scientific approach has focused on visualizing and analyzing the shape and electrostatics of molecular 3D structures to inform and guide the advancement of pharmaceuticals and biotechnology. OpenEye integrated its applications and toolkits into Orion, the only cloud-native, fully integrated molecular design platform. Combining unlimited computation and storage with powerful tools for data sharing, visualization and analysis in an open development platform, Orion offers unprecedented capabilities for drug discovery and optimization. Founded in 1997, OpenEye was acquired by Cadence Design Systems (NASDAQ: CDNS) in August 2022. OpenEye is headquartered in Santa Fe, New Mexico, with offices in Boston, Massachusetts; Cologne, Germany; and Tokyo, Japan.
Job Description
Principal UI Engineer to work on cutting-edge cloud computing, C++/Python development, and advanced MD simulation techniques to make a major impact in drug discovery. The position is located in the Boston, MA office and requires onsite presence.
Requirements
- BS in computer science/engineering, biology/chemistry or similar with a minimum of 7 years of experience
- MS with a minimum of 5 years of experience
- PhD with a minimum of 1 year of experience
- Expert in JavaScript/Typescript/CSS/HTML
- Experience with Vue, Pinia/VueX and application frameworks such as Nuxt.js / Next.js
- Experience in Life Sciences, HPC, Python, AWS, Web Workers, WebAssembly, and WebGL
- Experience with unit & end-to-end testing, CI/CD, source control, code review, comfortable using command line interfaces
- Strong background of computer science fundamentals (data structures, algorithms)
- Passionate to learn and explore new technologies and demonstrates good analysis and problem-solving skills
- Ability to establish a close working relationship with peers in development, science, design and customer success, often across time zones
- Take initiative to solve unexpected challenges during development
- Willing to expand their knowledge and skills in both technical and scientific areas
- Push to raise the bar while always operating with integrity
Benefits
- paid vacation
- paid holidays
- 401(k) plan with employer match
- employee stock purchase plan
- a variety of medical, dental and vision plan options
- bonus
- equity
