Xaira Therapeutics is seeking a Senior Research Associate Scientist in the Protein Engineering group to design, generate, and scale complex DNA assemblies for protein engineering and display teams. The ideal candidate will have extensive experience with combinatorial, designed, and naive library building, microbiological and protein level expertise to express & qualify them once built. This hands-on role requires NGS, protein biochemistry, and DNA assembly needs in mind when building complex libraries at speed.
Requirements
- Bachelor of science or master degree in Molecular Biology, Protein Biochemistry, or related fields
- 5+ years of industrial experience
- Hands-on experience with yeast display system and library building
- Cloning complex assemblies with multi-part golden gate, gibson, and other techniques
- Experience with DNA synthesis CROs
- High proficiency in yeast display to protein targets, soluble and membrane
- Proficiency in molecular and cell biology techniques, such as DNA extraction, PCR, enzymatic DNA treatments and library preparation QC for NGS
- Mammalian tissue culture
- Antibody engineering and discovery experience
- Flow cytometry experience (both analytical and sorting)
- Excellent analytical and problem-solving skills, with meticulous attention to detail
- Strong written and verbal communication skills
- Ability to work effectively in a collaborative, multidisciplinary team environment
Benefits
- Competitive compensation and benefits package
- Open, flexible, and friendly work environment
- Platform to develop long-term careers
- Bonus
- Equity