Senior Director, DMPK Project Leader

Centessa Pharmaceuticals is a new kind of pharmaceutical company that prioritizes data-driven decision making led by subject matter experts. We are seeking a Senior Director, DMPK Project Leader to ensure delivery of all DMPK related activities and support the understanding of pharmacokinetic, toxicokinetic, and ADME principles for the progression of drug candidates across the portfolio.

Requirements

• Ph.D. in Pharmaceutical Sciences, Pharmacology, or a related scientific field
• Minimum of 10 years of industry experience in a biotech or pharmaceutical setting
• Expert in DMPK sciences with knowledge of drug discovery and development processes
• Strong analytical and problem-solving skills
• Experience in DMPK project leadership
• Previous work in the discovery and/or development of CNS drug candidates
• Experience with regulatory submissions for small molecules
• Knowledge, experience, and proficiency in supporting GLP-compliant studies
• Good knowledge of all DMPK assays including the use of in silico tools for PK prediction
• Proficiency with Phoenix WinNonlin and other software for NCA and PK modeling in small molecule drug discovery and development
• Demonstrated ability to work cross-functionally and communicate scientific findings clearly and effectively
• Collaborative mindset and operates with a sense of urgency
• Strong, proactive communication skills

Benefits

• 401(k) plan
• Company-sponsored medical, dental, vision, and life insurance
• Generous paid time off
• Health and wellness program