Senior Scientist, Oligonucleotide Chemist

Join LGC as a Senior Scientist, Oligonucleotide Chemist, and help drive innovations in oligonucleotide chemistry. Based in our dynamic Innovation Hub team in Petaluma, CA, you will develop and improve methods for synthesis, deprotection, purification, modification, and analysis.

Requirements

• Master's degree in chemistry or a relevant field, or equivalent experience, with a minimum of 10 years of industrial experience in modified oligonucleotide chemistry or demonstrated equivalence.
• Extensive knowledge and practical experience with oligonucleotide chemistries, protocols, and analysis.
• Proficiency in predicting oligonucleotide impurity profiles resulting from processing changes.
• Detailed knowledge of deprotection schemes, resulting chemical conformations, and degradation products.
• Expertise in oligonucleotide purification chemistries.
• Proficiency in analytical techniques, particularly HPLC and mass spectrometry.
• Demonstrated extensive problem-solving experience.
• Ability to optimize complex chemical processes and adapt to shifting priorities in a fast-paced setting that values accuracy and precision.
• Data-driven decision-making skills.
• Excellent data analysis and interpretation abilities.
• Experience with quality control procedures and GMP regulations.
• Understanding of nucleic acid therapeutics and diagnostics applications.
• Strong organizational skills and attention to detail.
• Excellent written and verbal communication skills in English.

Benefits

• Health Insurance
• Dental Insurance
• Vision Insurance
• 401(k) Matching
• Life Insurance
• Paid Vacation
• Paid Holidays
• Sick Leave