Associate Director, Affinity Reagent Development and Characterization
Nautilus BiotechnologySan Carlos, California, United States
Posted March 20, 2026
Full Time
About the Company
Nautilus is a biotechnology company that is developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use.
Job Description
At Nautilus, we are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome.
Requirements
- PhD in biophysics, protein chemistry, structural biology, or similar field + 10 years experience (or postdoc + 5 years experience)
- 5+ years of management experience
- Demonstrated hands-on experience with affinity reagents, especially antibodies, including library panning (e.g. phase and/or ribosome-display) and affinity maturation
- Demonstrated experience using in silico and ML/AI tools to investigate and optimize affinity reagents
- Experience with interaction characterization tools such as SPR and BLI and high throughput protein-protein interaction / reactome characterization tools
- Exceptional communication, collaboration, and presentation skills
- Strong leadership, strategic planning, and decision-making capabilities
Benefits
- Generous Paid Time Off
- 401k Matching
- Retirement Plan
- Four Day Work Week